Youtube daily report Mar 19 2018

Hello friends, today I bring you a delicious dish of Chinese cuisine, sweet and sour pork

There are different versions, today we are going to prepare one of the simplest

and on another occasion we will do the others. I hope you like it, we started.

For this recipe, we use pork, I am using loin,

but it is also worth any other part,

in addition it can be prepared with chicken or beef

To marinate, we put light soy sauce,

salt,

white pepper

a splash of Chinese rice wine, if you do not have it, nothing happens

an egg and we mix everything well

Cover and let marinate in the fridge at least 30 minutes

To coat it we will use a mixture, half of multipurpose wheat flour and half of cornstarch

If you do not have cornstarch, you can use only wheat flour

To make it crisp, in plenty of vegetable oil we are going to make the double fried

The first on medium heat, about 160 ºC until the pork is cooked, it will take 4 to 5 minutes

The second fried over high heat, about 190 ºC until it is well browned and crispy

To make our sweet and sour sauce, in a pan with a splash of vegetable oil,

fry the garlic, It is optional

add some watter

rice vinegar,

ketchup,

light soy sauce,

sugar,

salt and mix everything well

Gradually add a mixture of cornstarch with water to thicken the sauce

Add the pork,

mix everything well and serve it immediately

It can be eaten alone or accompanied by freshly cooked white rice

Friends, you have already seen how easy it is prepared, its flavour is delicious

In the post of the recipe I leave more information about this and other versions

If you like it please "thumbs up" and to not loose any of my recipes

please subscribe to my channel. Bye, bye !!!

For more infomation >> Cerdo agridulce auténtica comida china - Chinese Sweet And Sour Pork "Tang Cu Li Ji" - Duration: 6:55.

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How Doctors Accidentally Discovered Psychiatric Drugs - Duration: 7:04.

[INTRO ♪]

A century ago, the idea that pharmaceuticals could treat mental illness

was considered fringe science—now, it's fundamental psychiatry.

That shift happened when effective drugs for conditions

like schizophrenia and depression were found in the 1950s—by accident.

Basically, some unexpected side effects in anesthesia boosters

and antibiotics gave birth to the entire field of psychopharmacology:

the study of how drugs affect mood and behavior.

Which means we have some serendipitous side effects

to thank for everything from Abilify to Zoloft.

You'd think drug development would begin with doctors studying an illness,

figuring out what's going wrong, then looking for compounds that might fix it.

Instead, things often happen in reverse—

unexpected side effects pop up when drugs are being tested

for one thing—and sometimes, those prove more interesting.

This was especially true a few decades ago in the early days of psychiatry,

when loose regulations made it easier to test drugs on people.

For example, the antipsychotic chlorpromazine

was first investigated as an antihistamine:

a drug that reduces immune reactions, including allergies.

Antihistamines also tend to have sedative effects,

so in 1952, French surgeon Henri Laborit thought that he could combine it

with anesthesia to induce a kind of 'artificial hibernation'

which would prevent patients from going into shock during surgery.

Instead he noticed that it made them calm and disinterested

without putting them to sleep like other antihistamines.

Based on his observations, he convinced psychiatrists at a military hospital

to try it on patients exhibiting psychosis:

a break from reality that's a common symptom

of certain mental disorders, like schizophrenia.

The calming effects on the first patient,

a 24 year old man named Jacques, were immediate.

20 days later, he was able to leave the hospital

and "resume normal life"—something basically unheard of at the time.

Over the next few years, the drug spread across the world,

helping thousands of mentally ill patients leave institutions.

But it wasn't until over a decade later that researchers discovered

how it works: by blocking receptors for the compound dopamine,

one of the brain's most important neurotransmitters sending signals between neurons.

Chlorpromazine is not a cure-all for all people with schizophrenia,

but it led to further research on the role of dopamine in psychosis

and eventually the development of newer meds

like aripiprazole, better known as Abilify.

And it's credited for beginning the cultural shift in psychiatric science

towards understanding the chemical basis of disorders.

Prior to chlorpromazine, the focus was on electrical activity

in the brain—which is why shock therapy was so popular.

So this discovery paved the way for research on all kinds of drugs for mental disorders.

And that includes the first antidepressant,

which was also discovered through unexpected side effects.

At the time, doctors in New Jersey were trying to find

new antimicrobials to fight tuberculosis.

So they were tinkering with hydrazine,

a rocket fuel that is the precursor to some drugs,

because they were able to obtain it cheaply after World War II ended.

Because what else are you going to do with all that extra fuel, I guess?

They kept trying slightly modified versions on volunteer patients with chronic TB,

and in 1952, they realized one variant—iproniazid—

had an entertaining side effect: improved mood.

Patients were described as literally "dancing in the halls

tho' there were holes in their lungs".

These euphoric effects were seen as a bad thing by the drug developers—

but New York psychiatrist Nathan Kline thought otherwise.

He was looking for something that would lift depressive states;

basically, to do the opposite of a drug like chlorpromazine.

So when he saw the energy iproniazid gave mice and people alike,

he begged the Jersey company to let him test it.

He and two of his colleagues led the first small psychiatric trial,

published in 1958, finding significant improvement

in 70 percent of their 17 depressed patients.

Soon it was all the rage, and for a few years,

it became the go-to antidepressant.

Doctors actually already knew what it did from studies on its use

as a treatment for tuberculosis.

In 1952, researchers found that it inhibits an enzyme

called monoamine oxidase or MAO.

What they didn't realize then is that MAO breaks down neurotransmitters

like serotonin which are involved in regulating mood.

So when you block MAO in the brain, levels of serotonin go up—

lifting people's spirits.

Iproniazid's use was short lived.

In 1961, the drug was withdrawn because of toxic effects on the liver.

But its popularity and effectiveness helped change the negative attitude

many psychiatrists had towards the idea of treating mental illness chemically.

And it wasn't the only serendipitous antidepressant discovery in the late 1950s.

Following on the success of that first drug we talked about,

Swiss psychiatrist Roland Kuhn was trying to find

the next antihistamine-based antipsychotic

when he discovered the tricyclic antidepressant imipramine.

It has three rings in its chemical structure—hence tricyclic.

Since it's somewhat similar to chlorpromazine in shape,

Kuhn and the pharmaceutical company he was working with

thought it might also treat psychosis.

But when Kuhn gave it to his psychotic patients,

it did not calm them—if anything, it made them manic.

It was only really helpful in his schizophrenic patients

who had severe depressive symptoms.

Based on these observations, he tested the new drug on roughly 100 patients

with depression, publishing his subjective summary of the results in 1957.

His findings were so promising that the tricyclic antidepressant quickly gained popularity.

Studies done in the 1960s showed that, like iproniazid,

it also increases the level of serotonin-based signaling in the brain,

but without inhibiting MAO.

Instead, it prevents neurons from sucking serotonin back up

after they release it, leaving more floating around.

MAO inhibitors and tricyclic antidepressants are still sometimes prescribed,

but not as commonly, since they have unwelcome side effects.

But even though they're less used now, they formed the rationale

for research into other drugs that could increase serotonin levels in the brain.

That includes the blockbuster antidepressants on the market today:

selective serotonin reuptake inhibitors like sertraline—also known as Zoloft—

which work a lot like tricyclic antidepressants but with fewer side effects.

Thanks in large part to all of these discoveries,

more than 60 different psychiatric drugs were available by the end of the 1970s,

including 22 calming drugs following on the heels of chlorpromazine

and 15 antidepressants inspired by imipramine.

And in general, they were foundational to our understanding

of the neurobiology of mental illness.

So now, pharmaceutical companies and scientists can go about

psychiatric drug discovery in the way that you would expect:

by building chemical compounds that hone in

on parts of our bodies that are off balance.

Which means more people with mental illnesses

have reason to dance in the halls—and are leading happier, healthier lives.

Thanks for watching this episode of SciShow Psych!

If you would like to learn more about how antidepressants work,

we have an episode on the science behind them.

[OUTRO ♪]

For more infomation >> How Doctors Accidentally Discovered Psychiatric Drugs - Duration: 7:04.

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Yes, if you want to set up a healthy lead generating pipeline for your on or offline sources.

Hi, do you want this money? It's for your business

I do want this money, yes, thank you.

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Il mio Cammino di Santiago | EP #14 - Duration: 10:46.

This is Finisterre. Here we are Muxia.

We meet again, Matteo.

Guys good morning, it's the 14th day, today we got to Finisterre, that's my alarm, great. Welcome to the new episode.

So today I need to change my room,

let's clean this up, let's go to another one.

Okay so I had to change my room cause apparently was taken yesterday and now

I have the same room. I just moved my stuff for nothing.

Great.

I'm gonna meet the guys at 8:45 at the reception.

We go to the airport rent the

Rent a car.

Go to Finisterre and Muxia.

Ahhhh my legs.

Here we are, Muxia. We were driving and we were saying it's not the same as

walking so we're really missing walking, you see all the landscaping driving by,

it's not the same thing and also something you miss is the smell

of the poo of the cows, it's ridiculous but, nature man.

Ocean time.

Muxia guys, north of Spain, it's one of the last two

destinations of the Santiago pilgrimage and we have Muxia here and Finisterre,

which we're going to visit a bit later. This is la Costa

de la muerte, verdad? Costa da Morte which means the cost of death, because a lot of

ships crashed against the rocks and a lot people died here, so that's where it

takes the name from.

I try to keep up with parkour, 2 weeks without, lost it.

The smell of the sea. Something I've been learning from this great experience is to enjoy things I've never enjoyed before.

I've seen the sea a thousand of times in my life,

I never enjoyed so much. There's really something after two weeks of walking in

nature, you know, without the usual routine,

it really makes you appreciate what we've been given as a gift.

Muxia, Spain.

So guys, this drone shot, seriously, every drone shot I take is the best for me.

It looks sick.

We visited this church, it's called la basilica de la Virgin de la Barca. In English

is the the basilica of the Virgin of the Ship, basically the

legend says that when Saint James reached Muxia, the Virgin appeared on

on a ship to welcome and greet the pilgrim.

Fisterre or Finisterre, from Finis Terrae, the end of the land, the end of the world. This is

one of the most remote points in the north of Spain, in Galicia, and it

represents the end of the pilgrimage, for the pilgrims, like us.

End of pilgrimage kilometre zero.

There is a tradition, there used to be a tradition where you get to Finisterre

and you burn your clothes and that is a sign of leaving your past behind and start a new life. It is now forbidden but people still do.

I think my favorite between, Muxia and Finisterre, Muxia wins.

Looking for a place to have some comida and we found a place with

arroz con leche, again which is what we were eating in Asturias, which

is rice with milk and caramel on top, yeah so we haven't found it in Galicia

yet but we found it today, so we might go there. And yes, after 15 restaurants we go

to the first one we've seen because they have the arroz con leche, just for that reason.

Guys, thanks for everything.

After nine months, beer.

Wow guys, Tio Indy, this is for you.

Arroz con leche.

We meet again, Matteo. Like after week.

This is part of the pilgrimage too, you meet friends and you leave them behind.

And we are back in Santiago,

so after Muxia and Finisterre we're back here, going to the service and then

we eat some food and finish the day off, I guess.

People, we have drunk, we've eaten, we're ready to go to bed, tomorrow early start again,

last day here in Santiago for me. It's been a good day,

be positive, keep smiling, whatever your problems are, that just a test to make you grow.

So keep believing, keep doing your things. God bless, see you tomorrow.

Introduction, so during the Camino you learn a lot of things, also magic tricks, like this one.

In the next episode.

We walked 334 kilometres, I'll see you in the UK.

We see around the world.

Follow the Adventures of my Camino de Santiago on YouTube.com/mamoair.

Subscribe now for the video notifications.

For more infomation >> Il mio Cammino di Santiago | EP #14 - Duration: 10:46.

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Do you have Mastercard? Soon you could use your body as a NIP 🔴 | NEWS AT THE MOMENT - Duration: 9:10.

I tell you how many of us do not We received the news when we were

young people who are going to implant a brand of the beast to all of us who do not

had that mark of the beast because no was going to be able to have this one may not be of

commercial transactions was not going to be able buy to be able to sell and some

Fortune tellers have said that this brand of beast was going to arrive and I just

find me with a note that I want share with all of you that I

seems to make this point clear about the mark of the beast but at a level

modern and at a completely legal level to put it in some way

then come with me please this this note of the portal money in image and

I'm going to read for all of you and we touch a little bit about the brand

of the beast of those who veto them from the who spoke to them at that time to

end of this year or early 2010 nine banking clients

will start to see the first cards biometrics for low segments

vice president of marketing and mastercard communication mexico and

Central America José Luis de la Vega explained that during

the 81 new banking convention will presented the first biometric card

for the base of the pyramid this part of the note the one that says the first

biometric card for the base of the pyramid

I want to make an emphasis here for explain to them that some theorists

mention the theme of the pyramid in the new world order and the issue of

mark of the beast the new world order continued with the

reading of the note says that it will help verify the identity of those who

receive government support the we present at the convention and we are

doing tests with a couple of institutions is a card like the

that we know but they have a small box for the cardholder

put your fingerprint and at that moment he recognizes he commented

in this way you can be 100% sure of who is using the

card and it really is who you are gave the benefit claimed the manager of

the company applied technology of the global steps industry

here I want to make another break and tell all of you what I

It seems regarding what this part of the

note I did not do in this way it can be 100% sure that those who

has used the card and that really it is to whom the benefit was given

informed the company manager of technology applied to the industry of

global payments is to say what they are trying or achieving or are looking for

achieve is that you can not use it card to anyone to make purchases

or make withdrawals this seems to be something for now

extremely safe and positive given the circumstances in which we are

living but you think of a future not too far away by technology

advancing by leaps and bounds like what up to this moment a kind of

global control through a system of payments is to say we can not like you

to the system at this time but in the end We can keep making money if someone

the more he charges it for us but in that new world order probably already

can not do that everyone will be able to be this owner of

your money from your food and under the pretext to prevent a theft because I'm not going to

allow to transfer in this case money to anyone else

2 continued with the note if I allow it to give you bill says what to look for is

simplicity and security the director assured today that today more

nearby is the segment leader decree however one of his

main focuses is to turn to fight the statistics on the use of

cash is something I also do not want make a very important emphasis says that

they want to avoid using cash and they claim that technological systems

they replace what we know today as currency or banknote no 80 and 85 for

One hundred percent of payments are made at home in cash and that is his true

purpose to reverse the equation is what they look for these technology leaders in

banks reverse the equation and that operations are increasingly being used

of the challenges is to increase the level of certainty to payments

besides help that all procedures that are carried out

safe and natural for that reduce frauds the most the way

that we are generating by accelerating all these tools so that in the future

transactions can be made nearby in a natural and safe way and minimizing

the frauds pointed out the vice president of marketing and communication for mexico

and Central America by master card so far the note so far the note

informative news friends at moment was commenting is a bit about

this matter It seems a bit risky to me

all our information already at biometric level remember you

that also here in Mexico is thinking about making a kind of

biometric census wanted to increase a new fee I wanted to invent a new

system that would allow this one to will allow the government to know who

we are what we spend where we live here and

now we are going to be returned from by yes deposited this system

this new cell phone all this technology that has come

developing about 20 years to date past giantess 2 by the way deposits

these technologies I'm almost sure they hear us from

some way they listen to us through the phone I do not want to be

I do not want to seem paranoid for everyone you but already and this information from

already made some note informative some video of someone who

they were spying on the phone he was talking to his brother

commented on the subject for example of a funeral

curiously after a few minutes Ads began to appear on

funerals not then of itself already we spy through the phone through the

coop to put the camera through many

systems not by the gps are no longer spying and well this allowing a

biometric system would not only give them access to this new world order for

who creates in the west new system that this looming that to govern the world is not

I would only give him access to know what I do with my time here doctor where he checked

which I like if I would not give them access also to my mind to my blood to my

body at levels that if we see it here in a few years we are practically for

thinking about cloning humans for ends of slavery makes me suggest

A lot of things this is the note and that's why it's left behind

you all say you have mastercard I could soon use your body your muni and

comes the advancing technology you need to know to be

informed like me and at the same time we are approaching a new

world order you have to observe very close what is happening in the world

to be aware and able to know that we should take and that we should not

do I wait for your opinion on this subject the biometric system

this one to know what you think about it to send greetings quickly to

pixar or consuelo garcía thank you very much and sorry we had a failure in the audio

the beggining I ask you an apology jesús ramírez liz

other oscar ortega says flores e álvaro ulises bautista alejandra salazar many

thank you always for being here alejandra leticia flowers thank you for sharing

this information at ease thanks thank you to you news friends increased my

name is at ease tears wished that this one have a great time we see each other in

the next informative note we are trying again at least

two formats this one I would like me to make some comments on how

they would like us to treat the news what news they like most are those of

blood and fire as well as the what almost war if you slip the

blood well an intermediate point between that so then I'm going to get the wait

of the visa says he wants to be sent greetings to kids health to axel and famous

Of course it's strange and he threw flowers thanks very good information with only

we go to the next note informative hours and until then

For more infomation >> Do you have Mastercard? Soon you could use your body as a NIP 🔴 | NEWS AT THE MOMENT - Duration: 9:10.

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Juice WRLD X Lil Peep Type Beat | Prod. By Georgie - Duration: 3:05.

(Prod. by Georgie)