This video explains why more and more men prefer to use Scrotal Application Of Testosterone
Cream Over Gels and Injections for their Testosterone Replacement Therapy.
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In this video I discuss the most optimal and most efficient delivery system for men undergoing
Testosterone Optimization Therapy.
More and more men prefer to use Scrotal Application Of Testosterone Cream Over Gels and Injections
for their TRT, and that is with good reason.
Let me explain.
Scrotal skin is thin and has high steroid permeability.
The cream we are talking about is a Testosterone cream at 200mg of micronized testosterone
per 1gram (20%) in a lipoderm base or versabase.
You can't apply any alcohol based preparation to the scrotum as it will burn and irritate the skin.
My Belgian pharmacist uses Pentravan® Cream Base by Fagron, a unique oil-in-water emulsion
with a liposomal matrix, which enables it to establish a greater rate and extent of
absorption of the drug than other transdermal bases.
Besides that, Pentravan® Cream Base is a true vanishing cream, leaving no sticky residue
and providing a cosmetically elegant skin feel.
It is preserved and fragrance-free.
Credits to dr.Keith Nichols, MD, for the exact formula.
This cream should be applied twice daily 'trans-scrotally' to a freshly shaven scrotum.
The exact, needed dose can easily and accurately be measured by a Topi-Click dispensing system,
delivering 0.25g of cream, containing 50mg of Testosterone per audible and tactile 'click'.
Typical dosing is 2 to 3 clicks, delivering 100 to 150mg testosterone twice a day.
With regard to transference, sexual contact should be avoided for 4 hours (as well as
showering) after application of the cream.
Studies have shown that testosterone administration to scrotal skin is well tolerated and produces
a dose-dependent peak serum testosterone concentration with a much lower dose
relative to non-scrotal transdermal route.
When you want to test your levels of testosterone, you should do this 5 hours after the application.
Here are some more advantages of using this method of TRT:
(1) It seems obvious that the chances of secondary exposure to others are much less, because
of the site of application.
(2) Because of the higher concentration, much smaller amounts of cream are needed.
(0.50 to 0.75g per application).
(3) Pharmacokinetic studies on the absorption of testosterone cream on the scrotal skin
show 8 times higher absorption rates than on the shoulders.
(4) The cream base is much better tolerated than the hydroalcoholic topical gels regarding
skin irritation and discomfort.
(5) Twice a day application insures less fluctuations in the testosterone concentrations in the blood.
With scrotal application there is only a smooth linear peak felt throughout the day.
(6) Higher DHT levels, are responsible for libido.
Twice daily application on the scrotum definitely produces the best libido boost and sexual
function enhancement.
Energy is great all day with the typical twice a day administration.
(7) More efficient in bringing up the testosterone levels in the high end of the normal range,
which is of course better to alleviate all the signs and symptoms of testosterone deficiency,
next to helping optimize the normal functioning of the male endocrine system, strengthening
the bones, being cardioprotective, keeping a high insulin sensitivity, and many more health benefits.
I know several men using this method of TRT and repeatedly have total testosterone levels
in the 1500-2000 range.
No need to say they are free of all low T symptoms and feel great.
(8) Using a small amount of testosterone cream as a method of TRT, brings along way more
easier options when traveling.
You do not have to travel, passing airport checks and so on, bringing along syringes,
needles, ampules, and more.
(9) Obviously there is no pain from injections, no injection site reactions like nodules and
lumps, which are not so rare, and that I already talked about in this video.
We can conclude that the scrotal administration of testosterone in a compounded cream formulation
provides higher bioavailability, a dose-dependent peak serum testosterone concentration, and
tolerability with a much lower dose relative to the non-scrotal transdermal route.
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